Breast cancer treated successfully with immune therapy

  • Breast cancer treated successfully with immune therapy

Breast cancer treated successfully with immune therapy

Results from this study suggest many women with this specific type of tumour do not receive any additional benefit from having chemotherapy in combination with endocrine therapy, compared to endocrine therapy alone.

For many breast cancer patients, one of the most hard treatment decisions is whether or not to go through chemotherapy.

"Moving forward, when women are making this decision, this study will help us put it into perspective and give them better advice next week than we were able to give them last week", said Litton, who attended the American Society of Clinical Oncology conference in Chicago where the results were discussed. "It'll be great news for a lot of patients because they will get similar outcomes with less toxic treatment".

Cancer experts agree with her assessment.

"It feels miraculous, and I am beyond amazed that I have now been free of cancer for two years", Ms Perkins said.

"You shouldn't do chemo unless you have to", added Dr. Jack Jacoub, medical oncologist and medical director at the MemorialCare Cancer Institute at the Orange Coast Medical Center in California.

While IM-MS nodes can be treated with radiation therapy, concerns about the side effects of increasing the radiation area to the chest has limited such use.

Previously in clinical trials, checkpoint inhibitors have proved ineffective against most breast cancers. While still in an experimental stage, doctors believe that the pioneering development could mark a "paradigm shift" in cancer research and alter the very way that we look at the deadly disease.

The 21-gene test has been used since 2003.

Although chemo does help extend life in many cancers, saving patients from the extra treatment could lessen the overall burden of the breast cancer. The cells go on to attack all the tumours and shrink them in size finally curing the 49 year old woman.

Women with scores of 10 or lower were considered not to need chemotherapy while those with scores 25 and over were considered to need it. Dr Rosenberg said if proven, it could be beneficial in nearly any form of cancer.

"Oncologists have been getting much smarter about dialing back treatment so that it doesn't do more harm than good", Steven Katz, a University of MI researcher who examines medical decision-making, told the Washington Post.

The challenge so far in cancer immunotherapy is it tends to work spectacularly for some patients, but the majority do not benefit.

Women can have the tendency to turn towards chemo, even if the results have a relatively small benefit, Albain says.

The researchers were specifically interested in women who scored 10 to 25 on the test - scores that fall in the range of a medium risk of the cancer returning after surgery.

While chemotherapy is being dropped for some cases, it's being increased for more aggressive cancers.

That's why it's great news to hear that doctors in the USA have just made an incredible scientific breakthrough through, curing a woman who was in the advanced stages of the disease.

Breast cancer is the most common form of cancer among women in the world, and hormone-receptor-positive, HER2-negative, node-negative cancer constitutes about half of the 1.7 million cases diagnosed yearly worldwide. For the group that had both hormone and chemotherapy, the rate was 84.3%, a difference that was not statistically significant.

"Patients should not make any changes to their treatment based off this study, and should always consult their doctors". That means more than 85,000 women a year can safely forgo chemotherapy.